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1

Clopidogrel (Plavix), a P2Y 12 receptor antagonist, inhibits bone cell function in vitro and decreases trabecular bone in vivo

Syberg, Susanne, Brandao-Burch, Andrea, Patel, Jessal J, Hajjawi, Mark, Arnett, Timothy R, Schwarz, Peter, Jorgensen, Niklas R, Orriss, Isabel R

Journal:

Journal of Bone and Mineral Research

Year:

2012

Language:

english

File:

PDF, 3.13 MB

english, 2012

2

Hypoxia stimulates osteoclast formation from human peripheral blood

Jennifer C. Utting, Adrienne M. Flanagan, Andrea Brandao-Burch, Isabel R. Orriss, Timothy R. Arnett

Journal:

Cell Biochemistry and Function

Year:

2010

Language:

english

File:

PDF, 372 KB

english, 2010

3

Inhibition of osteoblast function in vitro by aminobisphosphonates

Isabel R. Orriss, Michelle L. Key, Kay W. Colston, Timothy R. Arnett

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

4

Hypoxia is a major stimulator of osteoclast formation and bone resorption

Timothy R. Arnett, Daniel C. Gibbons, Jennifer C. Utting, Isabel R. Orriss, Astrid Hoebertz, Martin Rosendaal, Sajeda Meghji

Journal:

Journal of Cellular Physiology

Year:

2003

Language:

english

File:

PDF, 211 KB

english, 2003

5

Hypoxia stimulates vesicular ATP release from rat osteoblasts

Isabel R. Orriss, Gillian E. Knight, Jennifer C. Utting, Sarah E.B. Taylor, Geoffrey Burnstock, Timothy R. Arnett

Journal:

Journal of Cellular Physiology

Year:

2009

Language:

english

File:

PDF, 278 KB

english, 2009

6

P2Y receptors in bone

Isabel R. Orriss, Timothy R. Arnett

Journal:

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Year:

2012

Language:

english

File:

PDF, 134 KB

english, 2012

7

Osteoblast responses to nucleotides increase during differentiation

Isabel R. Orriss, Gillian E. Knight, Sam Ranasinghe, Geoffrey Burnstock, Timothy R. Arnett

Journal:

Year:

2006

Language:

english

File:

PDF, 735 KB

english, 2006

8

Inhibition of Osteoblast function by bisphosphonates

Isabel R. Orriss, Michelle L. Key, Kay W. Colston, Timothy R. Arnett

Journal:

Year:

2008

Language:

english

File:

PDF, 62 KB

english, 2008

9

Formation of bony structures by cultured long bone osteoblasts: potent inhibition by parathyroid hormone

Sarah Taylor, Isabel Orriss, Michelle Key, Jessal Patel, Timothy Arnett

Journal:

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

10

Extracellular nucleotides regulate the expression and activity of ecto-nucleotidases by osteoblasts

Isabel Orriss, Timothy Arnett

Journal:

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

11

The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors

Isabel R. Orriss, Michelle L. Key, Andrea Brandao-Burch, Jessal J. Patel, Geoffrey Burnstock, Timothy R. Arnett

Journal:

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

12

Purinergic signalling and bone remodelling

Isabel R Orriss, Geoffrey Burnstock, Timothy R Arnett

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 392 KB

english, 2010

13

Hypothermia inhibits osteoblast differentiation and bone formation but stimulates osteoclastogenesis

Jessal J. Patel, Jennifer C. Utting, Michelle L. Key, Isabel R. Orriss, Sarah E.B. Taylor, Philip Whatling, Timothy R. Arnett

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

14

Purinergic signalling in the musculoskeletal system

Burnstock, Geoffrey, Arnett, Timothy R., Orriss, Isabel R.

Journal:

Purinergic Signalling

Year:

2013

Language:

english

File:

PDF, 850 KB

english, 2013

15

Role of the P2Y 13 Receptor in the Differentiation of Bone Marrow Stromal Cells into Osteoblasts and Adipocytes

Biver, Galadrielle, Wang, Ning, Gartland, Alison, Orriss, Isabel, Arnett, Timothy R., Boeynaems, Jean-Marie, Robaye, Bernard

Journal:

Year:

2013

Language:

english

File:

PDF, 1.83 MB

english, 2013

16

Generation of rodent and human osteoblasts

Taylor, Sarah E B, Shah, Mittal, Orriss, Isabel R

Journal:

BoneKEy Reports

Year:

2014

Language:

english

File:

PDF, 5.48 MB

english, 2014

17

Extracellular Nucleotides Block Bone Mineralization in Vitro : Evidence for Dual Inhibitory Mechanisms Involving Both P2Y 2 Receptors and Pyrophosphate

Orriss, Isabel R., Utting, Jennifer C., Brandao-Burch, Andrea, Colston, Kay, Grubb, Barbara R., Burnstock, Geoffrey, Arnett, Timothy R.

Journal:

Year:

2007

Language:

english

File:

PDF, 437 KB

english, 2007

18

The role of purinergic signalling in the musculoskeletal system

Orriss, Isabel R.

Journal:

Autonomic Neuroscience

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

19

Acidosis Is a key regulator of osteoblast ecto-nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity

Orriss, Isabel R., Key, Michelle L., Hajjawi, Mark O.R., Millán, José L., Arnett, Timothy R.

Journal:

Journal of Cellular Physiology

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

20

The P2Y 6 Receptor Stimulates Bone Resorption by Osteoclasts

Orriss, Isabel R., Wang, Ning, Burnstock, Geoffrey, Arnett, Timothy R., Gartland, Alison, Robaye, Bernard, Boeynaems, Jean-Marie

Journal:

Year:

2011

Language:

english

File:

PDF, 3.76 MB

english, 2011

21

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1−/− mice

Hajjawi, Mark O.R., MacRae, Vicky E., Huesa, Carmen, Boyde, Alan, Millán, José Luis, Arnett, Timothy R., Orriss, Isabel R.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

22

Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro

Hajjawi, Mark O. R., Patel, Jessal J., Corcelli, Michelangelo, Arnett, Timothy R., Orriss, Isabel R.

Journal:

Purinergic Signalling

Year:

2016

Language:

english

File:

PDF, 4.29 MB

english, 2016

23

Editorial overview: Musculoskeletal: Where are we with treating musculoskeletal disorders?

Orriss, Isabel R, MacRae, Vicky E

Journal:

Current Opinion in Pharmacology

Year:

2016

Language:

english

File:

PDF, 229 KB

english, 2016

24

Pyrophosphate: a key inhibitor of mineralisation

Orriss, Isabel R, Arnett, Timothy R, Russell, R Graham G

Journal:

Current Opinion in Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

25

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

Orriss, Isabel R., Arnett, Timothy R., George, Jacob, Witham, Miles D.

Journal:

Experimental Cell Research

Year:

2016

Language:

english

File:

PDF, 2.95 MB

english, 2016

26

Activation of the P2Y 2 receptor regulates bone cell function by enhancing ATP release

Orriss, Isabel R, Gueneri, Dilek, Hajjawi, Mark Or, Shaw, Kristy, Patel, Jessal J, Arnett, Tim R

Journal:

Journal of Endocrinology

Year:

2017

Language:

english

File:

PDF, 2.31 MB

english, 2017

27

Optimisation of the differing conditions required for bone formationï¿½inï¿½vitro by primary osteoblasts from mice and rats

Orriss, Isabel, Hajjawi, Mark, Huesa, Carmen, MacRae, Vicky, Arnett, Timothy

Journal:

International Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 988 KB

english, 2014

28

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis

Javaheri, Behzad, Poulet, Blandine, Aljazzar, Ahmed, de Souza, Roberto, Piles, Miriam, Hopkinson, Mark, Shervill, Elaine, Pollard, Andrea, Chan, Boris, Chang, Yu-Mei, Orriss, Isabel R., Lee, Peter D.,

Journal:

Year:

2017

Language:

english

File:

PDF, 3.27 MB

english, 2017

29

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms

Patel, Jessal J., Zhu, Dongxing, Opdebeeck, Britt, D'Haese, Patrick, Millán, José L., Bourne, Lucie E., Wheeler-Jones, Caroline P.D., Arnett, Timothy R., MacRae, Vicky E., Orriss, Isabel R.

Journal:

Journal of Cellular Physiology

Year:

2017

Language:

english

File:

PDF, 5.75 MB

english, 2017

30

Metabolic properties of the osteoclast

Arnett, Timothy R., Orriss, Isabel R.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.98 MB

english, 2017

31

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

Orriss, Isabel R., Lanham, Stuart, Savery, Dawn, Greene, Nicholas D. E., Stanier, Philip, Oreffo, Richard, Copp, Andrew J., Galea, Gabriel L.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.42 MB

english, 2018

32

Purinergic Signaling in Bone

Jørgensen, Niklas Rye, Adinolfi, Elena, Orriss, Isabel, Schwarz, Peter

Journal:

Journal of Osteoporosis

Year:

2013

Language:

english

File:

PDF, 1.13 MB

english, 2013

33

The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels

Brandao-Burch, Andrea, Key, Michelle L., Patel, Jessal J., Arnett, Timothy R., Orriss, Isabel R.

Journal:

Frontiers in Endocrinology

Year:

2012

Language:

english

File:

PDF, 960 KB

english, 2012

34

The in vitro behaviour of canine osteoblasts derived from different bone types

Meeson, Richard L., Perpétuo, Inês P., Parsons, Kevin, Orriss, Isabel R., Shah, Mittal, Pitsillides, Andrew A., Doube, Michael

Journal:

BMC Veterinary Research

Year:

2019

Language:

english

File:

PDF, 3.48 MB

english, 2019

35

The in vitro behaviour of canine osteoblasts derived from different bone types

Meeson, Richard L., Perpétuo, Inês P., Parsons, Kevin, Orriss, Isabel R., Shah, Mittal, Pitsillides, Andrew A., Doube, Michael

Journal:

BMC Veterinary Research

Year:

2019

File:

PDF, 3.48 MB

2019

36

Extracellular pyrophosphate: The body's “water softener”

Orriss, Isabel R.

Journal:

Year:

2020

Language:

english

File:

PDF, 9.44 MB

english, 2020

37

Extracellular Nucleotides Regulate Arterial Calcification by Activating Both Independent and Dependent Purinergic Receptor Signaling Pathways

Opdebeeck, Britt, Orriss, Isabel R., Neven, Ellen, DâHaese, Patrick C., Verhulst, Anja

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.23 MB

2020